负压封闭引流联合灌洗治疗感染软组织火器伤早期疗效的初步实验观察
《创伤外科杂志》[ISSN:/CN:]
- 期数:
- 2011年13卷04期
- 页码:
- 340-343
- 栏目:
- 基础研究
- 出版日期:
- 2011-12-19
文章信息/Info
- Title:
- Effect of vacuum sealing drainage with irrigation in the treatment of the infected firearm wounds
- Author(s):
- ZHAO Donghua; LIU Xingyan; GE Baofeng; et al.
- Institute of Orthopaedics,Lanzhou General Hospital of Lanzhou Military Command,Lanzhou 730050,China
- 分类号:
- R 605；R 641
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 【摘要】目的 探讨负压封闭引流（VSD）联合灌洗治疗感染火器伤的早期疗效。方法 18头猪枪击致伤右后肢，前2天不做任何治疗以造成感染火器伤。第3天行有限清创后，随机分为对照组（常规处理）、VSD组和实验组（VSD联合灌洗治疗）,每组6头。比较3组各时间点伤道细菌计数、外周血中白细胞和内毒素含量的变化，并行常规病理学观察。结果 与对照组和VSD组比较，实验组伤道细菌计数、外周血白细胞和内毒素含量迅速下降，病理学显示组织炎症反应明显减轻、组织修复快。结论 采用VSD联合灌洗对感染火器伤进行早期救治，能迅速控制感染、减轻全身反应、为尽早修复重建创造良好的软组织条件。
参考文献/References
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［2］Murray CK.Epidemiology of infections associated with combatrelated injuries in lraq and Afghanistan［J］.J Trauma,2008,64（3）:S232-238.
［3］Gabriel A,Shores J,Heinrich C,et al.Negative pressure wound therapy with instillation: a pilot study describing a new method for treating infected wounds［J］.Int Wound J,2008,5(3):399-413.
［4］Orgill DP,Manders EK,Sumpio BE,et al.The mechanisms of action of vacuum assisted closure: More to learn［J］.Surgery,2009,146(1):40-51.
［5］Anglen JO.Comparison of soap and antibiotic solutions for irrigation of lowerlimb open fracture wounds: a prospective,randomized study［J］.J Bone Joint Surg(Am),2005,87(7):1415-1422.
备注/Memo
- 备注/Memo:
- -
