严重创伤后凝血功能检查的研究和应用
《创伤外科杂志》[ISSN:/CN:]
- 期数:
- 2010年06期
- 页码:
- 555-555
- 栏目:
- 综述
- 出版日期:
- 2010-12-30
文章信息/Info
- Title:
- Research and application progress of examination on coagulation function in trauma patients
- 作者:
- 范铭兴；嵇武
- 210002江苏，南京，南京大学医学院临床学院，南京军区南京总医院，解放军普通外科研究所
- Author(s):
- FAN Mingxing; JI Wu
- Clinical School of Medical College of Nanjing University，General Hospital of Nanjing Command,Nanjing210002,China
- 分类号:
- R640.4
- DOI:
- -
- 文献标识码:
- A
- 摘要:
- 凝血机制障碍是妨碍严重创伤病人出血无法控制和死亡的重要原因。凝血机制受多方面因素调节，对于严重创伤病人，因为存在低血容量、低体温和代谢性酸中毒，常规的实验室检查往往存在各自的局限性。正确认识凝血功能检查的临床意义，综合分析可能影响凝血指标的相关因素，是合理治疗创伤病人的基础。
参考文献/References
［1］王革非,任建安,张文波，等.腹腔负压填塞在腹腔感染合并腹腔大出血中的应用［J］.医学研究生学报,2008,21(10):1053-1055.
［2］龚剑峰,朱维铭.低温酸中毒与凝血机制障碍［J］.中国实用外科杂志,2010,30(2):96-98.
［3］毛一雷,孙永亮.外科病人术前凝血指标异常的临床意义及对策［J］.中国实用外科杂志,2010,30(2):84-86.
［4］Arkin CF,Adcock DM,Ernst DJ,et al.National committee for clinical laboratory standards.collection,transport,and processing of blood specimens for testing plasmabased coagulation assays: approved guideline［M］.4th ed.Wayne Pa:NCCLS，2003：21-24.
［5］Martini WZ,Cortez DS,Dubick MA,et al.Thrombelastography is better than PT,aPTT,and activated clotting time in detecting clinically relevant clotting abnormalities after hypothemia,hemorrhagic shock and resuscitation in pigs［J］.Trauma,2008,65(3):535-543.
［6］马海梅，张会英，张伯松,等.创伤骨科病人围手术期凝血、纤溶活性的临床观察［J］.中华检验医学杂志,2003,26(5):284-286.
［7］Wolberg AS,Meng ZH,Monroe DM III,et al.A systematic evaluation of the effct of temperature on coagulation enzyme activity and platelet function［J］.Trauma,2004,56(6):1221-1228.
［8］Krause KR,Howells GA,Buhs CL,et al.Hypothermiainduced coagulopathy during hemorrhagic shock［J］.Am Surg,2000,66 (4):348-354.
［9］Dirkmann D,Hanke AA,Gorlinger K,et al.Hypothermia and acidosis synergistically impair coagulation in human whole blood［J］.Anesth Analg,2008,106(6):1627-1632.
［10］Borris LC,Breindahl M,Ryge C,et al.Prothrombin fragment 1+2 in urine as an indicator of sustained coagulation activation after total hip arthroplasty［J］.Thromb Res,2007,121(3):369-376.
［11］Aibiki M,Fukuoka N,Umakoshi K,et al.Serum albumin levels anticipate antithrombin III activities before and after antithrombin III agent in critical patients with disseminated intravascular coagulation［J］.Shock,2007,27(2):139-144.
［12］Luddington RJ.Thrombelastography/thromboelastometry［J］.Clin Lab Haematol,2005,27(2):81-90.
［13］Jeger V,Zimmermann H,Exadaktylos AK.Thrombelastography in trauma, the closer the better［J］.Trauma,2010,68(2):508.
［14］Jeeji R,Dutta S.Pitfall in interpretation of TEG results［J］.Eur J Anaesthesiol,2008,25(8):693-694.
［15］蒋忠,马正良,靳艳卿,等.终末期肝硬化肝移植术中凝血功能的调控［J］.临床麻醉学杂志,2008,24(4):297-299.
［16］陆志强,陈宇,梁永年,等.盐酸替罗非班修饰的血栓弹力图与血纤维蛋白原浓度的相关性［J］.临床麻醉学杂志,2007,23(5):376-378.
［17］Zambruni A,Thalheimer U,et al.Thromboelastography with citrated blood: comparabiliy with native blood,stability of storage and effct of repeated sampling［J］.Blood Coagul Fibrinolysis,2004,15(1):103-107.
［18］Tieu BH,Holcomb JB,Schreiber MA.Coagulopathy:its pathophysiology and treatment in the injured patient［J］.World J Surg,2007,31(5):1055-1064.
备注/Memo
- 备注/Memo:
- 全军医药卫生科研专项基金资助（08Z007）
